Lenterra Process Development Station
November 13, 2026 2026-11-13 16:39Lenterra Process Development Station
Lenterra Process Development Station (LPDS)
Lenterra Process Development Station is a benchtop instrument for
characterization of powders, liquids, slurries or other media being processed in a miniature mixing device. The media properties are characterized in real-time by a DFF sensor in a specific location within the mixing bowl. Time evolutions of force pulses exerted by the moving media upon the sensor and the coefficient of variation are recorded as metrics that are used for characterization of the material and process. In addition, impeller torque is dynamically measured using a rotary torque sensor. The device is particularly useful in a formulation development in pharmaceutical high shear wet granulation (HSWG).
The device is a combination of a benchtop Lenterra Mini-Mixer and Lenterra Inline Rheometer where a Drag Force Flow sensor is positioned at a desired location inside the mixer using a 3D precision translation stage (probe positioning system) and an appropriate probe adapter.
Using a small volume of material and QbD approach, LPDS can determine:
- Excipient variability
- Formulation variability
- Processing end point
- Critical Material Attributes (CMAs) and Critical Process Parameters (CPPs)
