News
November 8, 2021 2021-11-22 3:53News
Join us at the 66th Battery Symposium on booth 4
October 2025
We are pleased to announce that our representative in Japan, Takashi Nishimura (Reifycs Analytical Co.,Ltd.) will be exhibiting our Lenterra Inline Rheometer (LIR) and Drag Force Flow (DFF) sensor in the upcoming 66th Battery Symposium. The symposium will take place at Aichi Industry & Labor Center (WINC AICHI), Nagoya, Japan between November 18 -20, 2025.
According to Symposium Chair Professor Nobuyuki Imanishi: “Battery technology is a vital foundation that supports our everyday lives, and its importance continues to grow each year… The Battery Symposium aims to facilitate active discussions and the exchange of information on cutting-edge research findings and technological developments…”
Meet us at the booth #4 (on the 5th floor of WINC AICHI) to discuss your material characterization challenges and needs and to learn how Lenterra’s innovative technology can support your work. We look forward to seeing you there.
About Lenterra
Lenterra Inc., a New Jersey corporation, a developer of innovative micro-optical sensing technologies for mechanical forces in gases and liquids, his recently expanded its portfolio to powder characterization and powder flow measurements. Company’s flagship product – Lenterra Inline Rheometer (LIR) – is a unique instrument that employs patented Drag Force Flow (DFF) sensor and is capable to continuously monitor flow force, powder uniformity and temperature during processing. With years of experience, Lenterra is well skilled in addressing user’s individual flow characterization challenges, focusing on delivering a reliable solution for in-process material characterization, formulation development, scale-up, quality control, or other areas. More at www.lenterra.com.
Lenterra has developed a methodology for water content optimization in HSWG using its inline rheometer
July 2025
The company has completed a study measuring fingerprints for granulations of acetaminophen formulations with different API content and varied water addition amount using Lenterra Inline Rheometer (LIR). The fingerprints were compared with results of PSD analysis of the powder released after granulation and with the tablet dissolution tests. The comparison demonstrated a strong correlation between salient features of the fingerprints measured by LIR and particle size distributions for different water amounts added during granulation. Based on the measured process fingerprints, it was possible to reliably identify the water amount that is optimal for granulation. In addition, a correlation was found between the time when a characteristic feature appears on the LIR measurements and dissolution times of the tablets. The technology also identified the time interval that is suitable for ending granulation and determination of the end point. Overall, the study highlighted excellent capabilities of LIR as a tool for formulation development, scale-up, as well as real-time monitoring and control of HSWG.
The results were reported on at the 11th International Granulation Workshop, Hamburg, Germany on July 2nd, 2025 (https://www.sheffield.ac.uk/media/97581/download?attachment). The paper can be found here.
About Lenterra
Lenterra Inc., a New Jersey corporation, a developer of innovative micro-optical sensing technologies for mechanical forces in gases and liquids, his recently expanded its portfolio to powder characterization and powder flow measurements. Company’s flagship product – Lenterra Inline Rheometer (LIR) - is a unique instrument that employs patented Drag Force Flow (DFF) sensor and is capable to continuously monitor flow force, powder uniformity and temperature during processing. With years of experience, Lenterra is well skilled in addressing user’s individual flow characterization challenges, focusing on delivering a reliable solution for in-process material characterization, formulation development, scale-up, quality control, or other areas. More at www.lenterra.com.
Lenterra will be presenting on the International Granulation Workshop in Hamburg, Germany
June 2025
We will deliver an oral presentation “Correlation of granule and tablet properties with real-time in-line DFF sensor measurements in HSWG” at the 11th International Granulation Workshop, Hamburg, Germany on July 2nd, 2025 (https://www.sheffield.ac.uk/media/97581/download?attachment). We will present real-time measurements of acetaminophen granulation in Lenterra Mini Mixer.
Granulation fingerprints measured by our inline rheometer (LIR) were collected for variety of API concentrations and amount of water added. A strong correlation was observed between salient features of the measured signals and particle size distributions for different water contents, allowing for identification of optimal amount of water. The result was confirmed by the tablet dissolution measurements. In addition, a correlation was found between the time when a characteristic feature (a minimum of CVFPM and a maximum of MFPM) appears on the measured evolutions and the tablet dissolution times. The technology also allowed to identify the time interval for the granulation end point. The results of this study indicate that LIR can be used as a tool for formulation development, scale-up, as well as for real-time monitoring and control of high shear wet granulation
About Lenterra
Lenterra Inc., a New Jersey corporation, a developer of innovative micro-optical sensing technologies for mechanical forces in gases and liquids, his recently expanded its portfolio to powder characterization and powder flow measurements. Company’s flagship product – Lenterra Inline Rheometer (LIR) - is a unique instrument that employs patented Drag Force Flow (DFF) sensor and is capable to continuously monitor flow force, powder uniformity and temperature during processing. With years of experience, Lenterra is well skilled in addressing user’s individual flow characterization challenges, focusing on delivering a reliable solution for in-process material characterization, formulation development, scale-up, quality control, or other areas. More at www.lenterra.com.
Lenterra Inline Rheometer (LIR) Predicted Tablet Properties in a Study by University of Birmingham and GSK Ware
August 2024
A study published recently in the International Journal of Pharmaceutics (https://www.sciencedirect.com/science/article/pii/S0378517324006392) shows, in particular, that Lenterra in-line measurements provide unique and rich information about the granulation process. This study demonstrates that the Lenterra Inline Rheometer (LIR) is capable of signaling the time instant at which the binding liquid is evenly distributed within the dry powder bed, which further reveals the initiation of particle agglomeration. Furthermore, the integrated force and force pulse magnitude (FPM) during the water addition phase are shown to be valuable measurements in approximating granule properties (such as specific energy and basic flowability energy) and predicting tablet tensile strength. The capability of predicting tablet tensile strength and compaction force from upstream data will minimize waste and eliminate operator trial runs to get the best compression machine settings.
“We are very excited to see that this joint UoB and GSK study demonstrated capabilities of Lenterra’s technology in prediction of table properties during high shear wet granulation. With this study we are even more confident that LIR will soon be widely recognized as a unique PAT tool for monitoring and control in pharmaceutical processing”, noted Vadim Stepaniuk, Director of Operations at Lenterra Inc.
About Lenterra
Lenterra Inc., a New Jersey corporation, a developer of innovative micro-optical sensing technologies for mechanical forces in gases and liquids, his recently expanded its portfolio to powder characterization and powder flow measurements. Company’s flagship product – Lenterra Inline Rheometer (LIR) - is a unique instrument that employs patented Drag Force Flow (DFF) sensor and is capable to continuously monitor flow force, powder uniformity and temperature during processing. With years of experience, Lenterra is well skilled in addressing user’s individual flow characterization challenges, focusing on delivering a reliable solution for in-process material characterization, formulation development, scale-up, quality control, or other areas. More at www.lenterra.com.
Indian Pharmaceutical Alliance Recommends Lenterra’s Drag Flow Force (DFF) Technology as a Sensitive PAT Tool for High-Shear Granulation
July 2024
The Guidance on Process Analytical Tools (PAT) on Oral Solids and API published by the Indian Pharmaceutical Alliance (IPA) in June 2024 identified Lenterra’s DFF technology as a more sensitive and precise PAT among six technologies recommended in the publication (https://www.ipa-india.org/wp-content/uploads/2024/06/Guidance_on_Process_Analytical_Tools_(PAT)_in_Oral_Solids_and_API.pdf).
“We are pleased to learn that Lenterra’s technology is recommended as a PAT by the IPA, the alliance of pharmaceutical companies of India. India is a major world market for pharmaceutical processing technologies, and we are looking forward to extending our footprint in India and the East in general” said Vadim Stepaniuk, Director of Operations at Lenterra Inc.
About Lenterra
Lenterra Inc., a New Jersey corporation, a developer of innovative micro-optical sensing technologies for mechanical forces in gases and liquids, his recently expanded its portfolio to powder characterization and powder flow measurements. Company’s flagship product – Lenterra Inline Rheometer (LIR) - is a unique instrument that employs patented Drag Force Flow (DFF) sensor and is capable to continuously monitor flow force, powder uniformity and temperature during processing. With years of experience, Lenterra is well skilled in addressing user’s individual flow characterization challenges, focusing on delivering a reliable solution for in-process material characterization, formulation development, scale-up, quality control, or other areas. More at www.lenterra.com.
Lenterra’s Technology Featured on PAT & QbD Conference in India
May 2022
Dr. Sanjay Sharma, VP & Head-Technology Transfer of Lupin Ltd., featured Lenterra’s LIR technology at an CPhI “PAT & QbD” conference, held in India on 20th April, 2022. In his invited presentation, Dr. Sharma presented POC studies of using LIR that were carried out at a Lupin manufacturing plant. Slides for Dr. Sharma presentation can be downloaded here.
“We are excited to see that Lenterra’s technology is positively evaluated at Lupin and we looking forward to continuing cooperation with the company,” said Valery Sheverev, President and CEO of Lenterra Inc., “Presentation of Dr. Sharma marks a significant step for LIR technology recognition in the pharmaceutical community.”
About Lenterra
Lenterra Inc., a New Jersey, USA corporation was founded as a developer of innovative micro-optical sensing technologies for flow force measurements in gases and liquids, later expanded to powder characterization and powder flow measurements. Company’s flagship product – Lenterra Inline Rheometer (LIR) - is a unique instrument that employs patented Drag Force Flow (DFF) sensor that enables continuous real-time monitoring of flow force, uniformity and temperature during processing and transport of materials. With years of experience, Lenterra is well qualified to address user’s individual flow characterization challenges, delivering relevant solutions for in-process material characterization, formulation development, scale-up, quality control, or other areas.
